As a principal cause of death, cardiovascular diseases take 1.7 million lives every year. Endothelial cells play a significant role in the cardiovascular system and can serve as a portent of the vascular system’s health and robustness. Therefore, as an investigator, I am motivated to discover the axiom hidden behind this enigma. 

    Through years of highly motivated and scrupulous research, I have developed substantial experience and enriched expertise in studying redox signaling in endothelial cells and have a strong track record of research productivity. Furthermore, my research focus has expended to 3 major fields: (1) understanding the molecular and cellular mechanisms that regulate vascular inflammation, endothelial dysfunction, pulmonary microvascular injury in sepsis, arterial vascular dysfunction, and atherosclerosis; (2) developing non-invasive methods to measure in vivo vascular function in small animal models to allow longitudinal study of changes in vascular function over the course of disease development and/or pharmacological interventions; and (3) exploring endothelial cell-targeted therapies for lung and cardiovascular diseases.

    With an excellent research environment in our laboratory, my research covers a wide range of fascinating fields and disciplines. We have expanded our research from endothelial cells to the broader aspects of human cardiovascular disease covering topics of cardiovascular physiopathology, redox biology, redox proteomics, and optical vascular imaging.